ERA

Endometrial Receptivity Array Test in Hyderabad

Have you been considering getting an endometrial receptivity array test (ERA) in Hyderabad? Endometrial Receptivity Analysis, commonly called ERA, is a specialised genetic test designed to assess the receptivity of a woman’s endometrium or womb lining. This analysis aims to pinpoint the ideal time for embryo implantation, also known as the window of implantation (WOI).

By personalising this critical period in the IVF cycle for each patient, ERA aims to optimise the chances of successful embryo implantation and subsequent pregnancy. However, like all medical procedures, ERA comes with its unique advantages, potential complications, and varied success rates. At White Rose Fertility, we ensure you make informed decisions about your fertility journey. We’re located in Madhapur & Financial District. Book an appointment for more information.

Understanding ERA

The endometrium plays a pivotal role in conception as it is where the embryo implants and grows. The endometrium undergoes several changes throughout a woman’s menstrual cycle, reaching its peak receptivity during the window of implantation. Traditionally, this period was believed to be between days 19-21 of a regular 28-day menstrual cycle. However, this window can vary significantly among women, which is where ERA comes into play.

ERA is a genetic test that involves analysing the expression of genes associated with endometrial receptivity. The test categorises the endometrium as receptive (ready for embryo implantation), pre-receptive (not yet ready), or post-receptive (past the optimal point). By establishing a personalised WOI for each patient, ERA aims to increase the probability of successful embryo implantation.

Indications for ERA

The use of ERA is particularly beneficial in some instances. These include:

Repeated Implantation Failure (RIF): If you have experienced multiple unsuccessful embryo transfer cycles despite transferring good-quality embryos, your doctor may recommend an ERA.
Unexplained Infertility: In cases where standard fertility investigations fail to identify a cause for infertility, an ERA may be conducted to assess endometrial receptivity.
Recurrent Pregnancy Loss (RPL): If you have experienced two or more miscarriages, your doctor may suggest an ERA to determine if the timing of embryo transfer could be a contributing factor.

The ERA Process

The process of ERA involves three key steps:

Endometrial Biopsy: This initial step involves a minor surgical procedure where a small sample of the endometrium, the lining of the uterus, is collected. The procedure is relatively quick and performed using a thin, flexible instrument called a pipelle. The pipelle is gently inserted through the cervix into the uterus to obtain a small tissue sample that contains cells from the endometrium.
Genetic Analysis: After the endometrial biopsy, the collected tissue sample undergoes genetic analysis in a laboratory setting. The genetic analysis may include various molecular biology methods, such as polymerase chain reaction (PCR), microarray analysis, or next-generation sequencing (NGS). By examining the expression patterns of these genes, scientists can gain insights into the receptivity of the endometrium, helping determine the optimal time for embryo implantation.
Personalised Embryo Transfer: Once the genetic analysis is complete and the results are obtained, your doctor will interpret the findings to determine your personalised window of implantation. This window represents the ideal timeframe during your menstrual cycle when your endometrium is most receptive to embryo implantation.

Complications of ERA

While ERA is generally safe, no medical procedure is entirely without risk. Some of the potential complications associated with ERA include:

Discomfort or Pain: You may experience mild discomfort during the endometrial biopsy.
Abnormal Bleeding: Some women may notice spotting or light bleeding after the procedure.
Infection: Although rare, there’s a slight infection risk following the biopsy.
Uterine Perforation: In extremely rare cases, the biopsy can lead to a hole in the uterus or uterine perforation.

The Success Rate of ERA

Research indicates that ERA has high sensitivity (0.99758) and specificity (0.8857) for determining endometrial receptivity status, indicating its potential to predict your personalised WOI accurately.

ERA offers a promising approach for personalising fertility treatments and potentially improving IVF success rates. However, it’s crucial to remember that every individual’s fertility journey is unique, and treatment plans should always be customised to suit your specific medical needs. Before deciding, consult your doctor about the possible benefits and risks of undergoing ERA.

Despite this, the role of ERA is still controversial and in grey area of science.

Why Choose White Rose Fertility?

White Rose Fertility is driven by a foundational belief that every person’s journey to parenthood is unique, requiring personalised medical care and treatment. Our fertility centres in Madhapur & Financial District, offer an extensive range of fertility treatments, including the advanced endometrial receptivity array test (ERA) in Hyderabad. This diagnostic tool has enhanced our ability to determine the optimal time for embryo implantation. Our team of consummate professionals, headed by expert clinicians, ensures that every step of your journey to parenthood is navigated with utmost care.

We are steadfast in our commitment to uphold the highest ethical standards in treatment. Maintaining complete transparency and open communication ensures that patient trust is central to our practice. Our comprehensive fertility treatments are evidence-based, guided by rigorous scientific research and recognised international guidelines. This dedication to ethical practices is evident in our treatments and our pricing structure, which we designed with affordability in mind. To know more about the ERA test cost in Hyderabad, reach out to us.

Begin your treatment journey with White Rose Fertility. Our patient-centric approach ensures you are supported through each stage of your fertility journey. Book a consultation with our team today – together, we can explore your fertility preservation options and build a personalised treatment plan tailored to your needs.

FAQs

What exactly is the use of ERA in fertility treatments?

ERA, or Endometrial Receptivity Analysis, provides crucial information about the best time for embryo implantation during an IVF cycle. This helps doctors to tailor treatment plans for each patient, increasing the chances of successful pregnancy. It can be beneficial if you’ve experienced failed IVF cycles in the past.

How does ERA contribute to successful pregnancies?

The advantage of ERA is that it identifies your ‘window of implantation’. This is when your endometrium (the lining of your womb) is most receptive to an embryo. By doing this, doctors can time the embryo transfer more accurately, potentially improving your chances of a successful pregnancy.

Is ERA recommended for couples with repeated failed IVF cycles?

Yes, ERA is often suggested for couples who have unfortunately experienced failed IVF cycles. It can provide valuable insight into why previous attempts may not have succeeded and help customise future treatment plans. However, like any medical procedure, your doctor must assess its suitability for your particular circumstances.

What are some things to consider when thinking about the ERA costing?

When considering ERA costing, remember it can potentially save money in the long run by reducing the number of failed IVF cycles. However, consider any additional costs for consultations and follow-up appointments that may be needed alongside the test.

Are there any risks or side effects associated with an ERA test?

ERA is generally safe, but like any medical procedure, it carries some risks. You might experience mild discomfort during the test or slight bleeding afterwards.

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